Система Orphus
Yuri Gleba
Position: Professor, Nomad Bioscience GmbH, Managing Director, Icon Genetics GmbH/Bayer AG, Halle, Germany; Director, International Institute of Cell Biology, National Academy of Sciences of Ukraine, Kyiv, Ukraine; Director, Institute of Cell Biology and Genetic Engineering, National Academy of Sciences of Ukraine, Kyiv, Ukraine.
Address: Institute of Cell Biology and Genetic Engineering, 148 Zabolotnoho Str., Kyiv 03143, Ukraine
Fax: +380-44-522-1786
E-mail: gleba<AT>icongenetics.de


1975 Ph.D. in Plant Physiology, Institute of Botany, National Academy of Sciences of Ukraine, Kyiv, Ukraine.
 
1980 Doctor of Sciences in Genetics, Leningrad State University, Saint Petersburg, Russia.


Scientific interests:

  • plant cell biology, genetics and physiology
  • plant genetics and biotechnology


Professional membership:

World Academy of Arts and Science (Rome)
European Academy (Academia Europaea, London)
German Academy Leopoldina (Halle)
Ukrainian Academy of Sciences (Kyiv)
Lithuanian Academy of Science
Bavarian Academy of Sciences (Munich)


Selected publications:

Articles in peer-reviewed journals:

FROLOVA OY, PETRUNIA IV, KOMAROVA TV, KOSORUKOV VS, SHEVAL EV, GLEBA YY, DOROKHOV YL. (2010) Trastuzumab-binding peptide display by Tobacco mosaic virus. Virology. 10;407(1):7-13

GILS M, MARILLONNET S, WERNER S, GRÜTZNER R, GIRITCH A, ENGLER C, SCHACHSCHNEIDER R, KLIMYUK V, GLEBA Y. (2007) A novel hybrid seed system for plants. Plant Biotechnol J. 2008 Apr;6(3):226-35.

GLEBA, Y., KLIMYUK, V., MARILLONNET, S. (2007) Viral vectors for the expression of proteins in plants. Curr. Opin. Biotechnol., 18, 134-141

GOLOVKIN, M., SPITSIN, S., ANDRIANOV, V., SMIRNOV, Y., XIAO, Y., POGREBNYAK, N., MARKLEY, K., BRODZIK, R., GLEBA, Y., ISAACS, S., KOPROWSKI, H. (2007) Smallpox subunit vaccine produced in planta confers protection in mice. Proc. Natl. Acad. Sci. USA, 104, 6864-6869

WERNER, S., MARILLONNET, S., HAUSE, G., KLIMYUK, V., GLEBA, Y. (2006) Immunoadsorbent nanoparticles based on a tobamovirus displaying protein A. Proc. Natl. Acad. Sci. USA, 103, 17678-17683

GIRITCH, A, MARILLONNET, S., ENGLER, C., VAN ELDIK, G., BOTTERMAN, J., KLIMYUK, V., GLEBA, Y. (2006) Rapid high-yield expression of full-size IgG antibodies in plants coinfected with noncompeting viral vectors. Proc. Natl. Acad. Sci. USA, 103, 14701-14706

SANTI, L., GIRITCH, A., R., ROY, C.J., MARILLONNET, S., KLIMYUK, V., GLEBA, Y., WEBB, R., ARNTZEN, C.J., MASON, H.S. (2006) Protection conferred by recombinant Yersinia pestis antigens produced by rapid and highly scalable plant expression system. Proc. Natl. Acad. Sci. USA, 103, 861-866

DOROKHOV, Y., FROLOVA, O., SKURAT, E., GASANOVA, T., IVANOV, P., RAVIN, N., SKRYABIN, K., MAKINEN, K., KLIMYUK, V., GLEBA, Y., ATABEKOV, J. (2006) A novel function for a ubiquitous plant enzyme pectin methylesterase: The enhancer of RNA silencing. FEBS Lett., 580, 3872-3878

DOROKHOV, Y., SKURAT, E., FROLOVA, O., IVANOV, GASANOVA, T., P., SHEVELEVA, A., RAVIN, N., MAKINEN, K., KLIMYUK, V., SKRYABIN, K., GLEBA, Y., ATABEKOV, J. (2006) Role of the leader sequence in tobacco pectin methylesterase secretion. FEBS Lett., 580, 3329-3334

KUCHUK, N., SYTNYK, K., VASYLENKO, M., SHAKHOVSKY, A., KOMARNYTSKY, I., KUSHNIR, S., GLEBA, Y. (2006) Genetic transformation of plastids of different Solanaceae species using tobacco cells as organelle hosts. Theor. Appl. Genet., 113, 519-527

GLEBA, Y., MARILLONNET, S., KLIMYUK, V., (2005) Magnifection – a new platform for expressing recombinant vaccines in plants. Vaccine, 23, 2042-2048

GLEBA, D., BORISJUK, N.V., BORISJUK, L., KNEER, R., POULEV, A., SKARZHYNSKAYA, M., DUSHENKOV, S., LOGENDRA, S., GLEBA, Y.Y., RASKIN, I. (1999) Use of plant roots for phytoremediation and molecular farming. Proc. Natl. Acad. Sci. USA, 96, 5973-5977

GLEBA, Y.Y. (1998) Plant Biotechnology. Soros Education J., 6, 3-8

GLEBA, Y. (1995) Cellular genetic engineering of plants. European Rev. 3: 113-117

Books:

SIDOROV, V.A., PIVEN, N.M., GLEBA, Y.Y., SYTNIK, K.M. (1985) Somatic Hybridization of Soalanaceae. Naukova Dumka, Kiev, 1-132

GLEBA, Y.Y., SYTNIK, K.M. (1984) Cellular Engineering of Plants. Naukova Dumka, Kiev, 1-160

GLEBA, Y.Y., SYTNIK, K.M. (1984) Protoplast Fusion. Springer, Berlin, Heidelberg, New York, 1-220

Book chapters:

WILKE, D., GLEBA, Y. (2006) Starting at the front end: processes for new renewables as feedstocks of the future. In: Feedstocks for the future, J. Bozell & M. Patel, eds., ACS Symposium Series 921, 27-39

KLIMYUK, V., MARILLONNET, S., KNAEBLEIN, J., MCCAMAN, M. GLEBA, Y.Y., (2005) Production of recombinant proteins in plants. In: Modern Biopharmaceuticals, J. Knaeblein,(ed.) Willey-VCH, Weinheim, vol. 2, 893-917

GLEBA, Y.Y., MARILLONNET, S., KLIMYUK, V. (2004) Design of safe and biologically contained transgenic plants: tools and technologies for controlled transgene flow and expression. In: Biotechnology and Genetic Engineering Reviews, Intercept, Wimborne, vol. 21, 325-367

GLEBA, Y.Y. (2004) New tools and technologies for controlled plant transgene expression and transgene flow: safety by design. J.P.H. Nap et al. (Eds.) In: Genomics for Biosafety in Plant Biotechnology, IOS Press, 77-89

GLEBA, Y.Y., SHLUMUKOV, L.R. (1990) Selection of somatic hybrids. In: Selection of Plant Cells. Dix, F.J., (ed.) VCH, Weinheim, New York, Basel, Cambridge, 257-286

NEGRUTIU, I., HINNISDAELS, S., MOURAS, A., GILL, B.S., DAVEY, M.R., GLEBA, Y.Y., SIDOROV, V.A., JACOBS, M. (1989) Somatic versus sexual hybridization: features, facts and future. Acta Bot. Neerl. 38: 253-272

GLEBA, Y.Y., SIDOROV, V.A., HOFFMANN, F. (1984) Mechanical isolation and single-cell culture of isolated protoplasts and somatic hybrid cells. In: Cell Culture and Somatic Cell Genetics. Vol. 1, Academic Press, New York, 405-413

EVANS, D.A., BRAVO, J.E., GLEBA, Y.Y. (1983) Somatic hybridization: fusion methods, recovery of hybrids, and genetic analysis. Intern. Rev. Cytol. Suppl. 16:143-160

GLEBA, Y.Y. (1978) Extranuclear inheritance investigated by somatic hybridization. In: T. Thorpe (ed.), Frontiers of Plant Tissue Culture, Int. Assoc. for Plant Tissue Culture, Calgary, 95-102


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