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Oleh Stasyk
Position: Senior Scientist, Acting Head of the Department of Cell Signaling, Deputy Director for Science; Institute of Cell Biology NASU. Address: 14/16 Drahomanov Str., Lviv, 79005, Ukraine Phone: +380 32 261 21 46 Fax: +380 32 261 21 08 Home page: go to >> E-mail: stasyk<AT>cellbiol.lviv.ua |
1992 B.S., M.S. in Biology, I. Franko National University, Lviv, Ukraine.
2004 Ph.D. in Cell Biology, Institute of Cell Biology, Lviv, Ukraine.
Scientific interests:
- Nutrient sensing in eukaryotic cells and cell signaling
- Mechanisms of autophagy and organelle homeostasis
- Anticancer therapies based on amino acid deprivation
Professional membership:
Ukrainian Society of Cell Biology (Member)
Ukrainian Biochemical Society (Member)
Ukrainian Science Club (Associated member)
Selected publications:
1. Y. P. Bobak, B. O. Vynnytska, Y. V. Kurlishchuk, A. A. Sibirny, and O. V. Stasyk. (2010).Cancer cell sensitivity to arginine deprivation in vitro is not determined by endogenous levels of arginine metabolic enzymes. Cell Biology International (in press).
2. B. O. Vynnytska, O. M. Mayevska, Y. V. Kurlishchuk, Y. P. Bobak, and O. V. Stasyk. (2010). Canavanine augments proapoptotic effects of arginine deprivation in cultured human cancer cells. Anticancer Drugs (in press).
3. O. G. Stasyk, M. Maidan, O. V. Stasyk, P. Van Dijck, J. M. Thevelein, and A. A. Sibirny. (2008) Identification of hexose transporter-like sensor HXS1 and functional hexose transporter HXT1 in the methylotrophic yeast Hansenula polymorpha. Eukaryotic Cell. 7(4):735-746.
4. O. G. Stasyk, T. van Zutphen, H.A. Kang, O. V. Stasyk, M. Veenhuis, and A. A. Sibirny (2007). The role of Hansenula polymorpha MIG1 homologues in catabolite repression and pexophagy. FEMS Yeast Research. 7(7):1103-1113.
5. O. S. Krasovska, O. G. Stasyk, V. O. Nahorny, O. V. Stasyk, N. Granovski, V. A. Kordium, O. F. Vozianov, A. A. Sibirny. (2007) Glucose-induced production of recombinant proteins in Hansenula polymorpha mutants deficient in catabolite repression. Biotechnology and Bioengineering. 97(4): 858-870.
6. O. V. Stasyk, O. G. Stasyk, R. D. Mathewson, J.-C. Farré, V. Y. Nazarko, O. S. Krasovska, S. Subramani, J. M. Cregg and A. A. Sibirny. (2006) Atg28, a novel coiled-coil protein involved in autophagic degradation of peroxisomes in the methylotrophic yeast Pichia pastoris. Autophagy 2(1), 30-38.
7. W. A. Dunn, Jr., J. M. Cregg, J. A. K. W. Kiel, I. J. van der Klei, M. Oku, Y. Sakai, A. A. Sibirny, O. V. Stasyk and M. Veenhuis. (2005) Pexophagy: The selective autophagy of Peroxisomes. Autophagy1(2), 75-83 (review).
8. O. V. Stasyk, O. G. Stasyk, J. Komduur, M. Veenhuis, J. M. Cregg, and A. A. Sibirny. (2004) A hexose transporter homologue controls glucose repression in the methylotrophic yeast Hansenula polymorpha. J. Biol. Chem. 279(9), 8116-8125.
9. O. V. Stasyk, I. J. van der Klei, A. R. Bellu, J. A. K. W. Kiel, S. Shen, J. M. Cregg, and M. Veenhuis. (1999). A Pichia pastoris VPS15 homologue is required in selective peroxisome autophagy. Current Genetics 36, 262-269.
10. M. A. Johnson, H. R. Waterham, G. P. Ksheminska, L. R. Fayura, J. L. Cereghino, O. V. Stasyk, M. Veenhuis, A. R. Kulachkovsky, A. A. Sibirny and J. M. Cregg. (1999). Positive selection of novel peroxisome biogenesis-defective mutants of the yeast Pichia pastoris. Genetics 151, 1379-1391.






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