Alla Grishok Position: Assistant Professor, Department of Biochemistry and Molecular Biophysics, Columbia University, New York. Address: Columbia University, College of Physicians & Surgeons, 701 West 168th Street, HHSC, Room 611, New York, NY 10032 Phone: +1-212-305-9893 Fax: +1-212-304-5707 Home page: go to >> E-mail: ag2691<AT>columbia.edu

1986 B.Sc. in Molecular Biology, Kyiv State University, Ukraine.
2001 Ph.D. in Cell Biology, University of Massachusetts, Worcester.

Scientific interests:

• contribution of RNA to regulation of gene expression through chromatin
• epigenetic phenomena in C. elegans

Honors and awards:

• The Anna Fuller Fund Fellowship in Molecular Oncology (2002)
• Harold M. Weintraub Graduate Student Award (2002)
• Dean’s Award for Outstanding Academic Achievement by a Graduate Student (UMass Worcester) (2003)
• The Damon Runyon Cancer Research Foundation Fellowship Award (2002-2005)
• The Leukemia and Lymphoma Society Special Fellow Award (2006-2009)
• The Arnold and Mabel Beckman Foundation Young Investigator Award (2008-2011)
• NIH Director’s New Innovator Award (2009-2014)

Selected publications:

1. Grishok, A., Hoersch, S., and Sharp, P.A. RNA interference and retinoblastoma-related genes are required for repression of endogenous siRNA targets in Caenorhabditis elegans. PNAS 105, 20386-20391 (2008).

2. Grishok, A., and Sharp, P.A. Negative regulation of nuclear divisions in Caenorhabditis elegans by retinoblastoma and RNA interference-related genes. PNAS 102, 17360-17365 (2005).

3. Grishok, A. RNAi mechanisms in C. elegans (review). FEBS Letters 579, 5932-5939 (2005).

4. Grishok, A., Sinskey, J.L. and Sharp, P.A. Transcriptional silencing of a transgene by RNAi in the soma of C. elegans. Genes & Dev 19, 683-696 (2005).

5. Grishok, A. and Mello, C. C. RNAi (Nematodes: Caenorhabditis elegans) (review). Advances in Genetics 46, 339-360 (2002).

6. Grishok, A., Pasquinelli, A.E., Conte, D., Li, N., Parrish, S., Ha, I., Baillie, D.L., Fire, A., Ruvkun, G. and Mello, C.C. Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing. Cell 106, 23-34 (2001).

7. Grishok, A., Tabara, H. and Mello, C.C. Genetic Requirements for Inheritance of RNAi in C. elegans. Science 287, 2494-2497 (2000).

8. Tabara, H., Sarkissian, M., Kelly, W.G., Fleenor, J., Grishok, A., Timmons, L., Fire, A. and Mello, C.C. The rde-1 gene, RNA interference, and Transposon Silencing in C. elegans. Cell 99,123-132 (1999).

9. Tabara, H., Grishok, A. and Mello, C.C. RNAi in C. elegans: Soaking in the Genome Sequence. Science 282, 430-431 (1998).

10. Neitz, M., Neitz, J. and Grishok, A. Polymorphism in the Number of Genes Encoding Long-Wavelength-Sensitive Cone Pigments among Males with Normal Color Vision. Vision Res. 35, 2395-2407 (1995).